Easychem is a professional PHMB manufacturer and supplier providing high-quality Polyhexamethylene Biguanide Hydrochloride (PHMB) for global industrial applications.
PHMB is a broad-spectrum antimicrobial polymer widely used for controlling bacteria, fungi and algae growth in various systems. Due to its excellent antimicrobial performance, water solubility and compatibility with many formulations, PHMB is used in water treatment, aquaculture, disinfectants, industrial cleaning, coatings and other antimicrobial applications.
We supply PHMB in different grades and concentrations, including PHMB solution and PHMB powder, with stable quality, competitive pricing and reliable bulk supply capability.
| Item | Information |
|---|---|
| Product Name | Polyhexamethylene Biguanide Hydrochloride |
| INCI Name | Polyaminopropyl Biguanide |
| CAS No. | 32289-58-0 |
| Other CAS Numbers | 27083-27-8 / 28757-47-3 / 133029-32-0 (PAPB) |
| Abbreviation | PHMB |
| Function | Antimicrobial Agent / Biocide / Preservative |
Note: In cosmetic ingredient references, PHMB is commonly identified by the INCI name Polyaminopropyl Biguanide, while the chemical substance is Polyhexamethylene Biguanide Hydrochloride (PHMB HCl).
PHMB (Polyhexamethylene Biguanide Hydrochloride) is a polymeric biguanide antimicrobial agent.
It works by disrupting microbial cell membranes, leading to the inhibition and elimination of microorganisms including:
Compared with traditional antimicrobial chemicals, PHMB provides:
PHMB is a broad-spectrum antimicrobial ingredient used in selected personal care formulations to help control microbial contamination and improve product preservation.
Due to its excellent antimicrobial efficiency, water compatibility and formulation flexibility, PHMB can be used in applications such as:
Personal Care Applications:
PHMB has been reported as an antimicrobial/preservative ingredient in cosmetic and personal care products, including cleansers, shampoos, conditioners and other rinse-off or leave-on applications.
Wet wipes contain a high percentage of water and nutrients that can support microbial growth. Therefore, effective preservation is essential to maintain product safety and shelf stability.
PHMB can be used as an antimicrobial ingredient in wet wipe formulations, including:
Types of Wet Wipes:
✔ Broad-spectrum antimicrobial protection
✔ Effective control of bacteria and fungi
✔ Good water solubility
✔ Low odor profile
✔ Compatible with aqueous formulations
✔ Suitable for long-term preservation systems
Besides personal care applications, PHMB can also be used in home care products requiring antimicrobial protection.
Applications include:
PHMB provides effective microbial control and helps maintain product quality during storage.
PHMB is used as an effective antimicrobial agent in water systems to control microbial growth and biofilm formation.
Applications include:
Benefits:
PHMB can be used in aquaculture applications for microbial control and maintaining water quality.
Typical applications:
Advantages:
PHMB is used as an antimicrobial ingredient in disinfectant formulations.
Applications:
Benefits:
PHMB can be incorporated into industrial products requiring microbial protection.
Applications:
It helps prevent:
PHMB and PHMG are both polymeric biguanide antimicrobial agents but have different chemical structures and application areas.
| PHMB | PHMG | |
|---|---|---|
| Full Name | Polyhexamethylene Biguanide Hydrochloride | Polyhexamethylene Guanidine Hydrochloride |
| CAS | 32289-58-0 | 57028-96-3 |
| Structure | Biguanide polymer | Guanidine polymer |
| Application | Disinfectants, industrial antimicrobial, water treatment | Industrial antimicrobial applications |
| Performance | Broad-spectrum antimicrobial activity | Strong antimicrobial activity |
| Parameter | PHMB | Benzalkonium Chloride (BKC) | Triclosan (TCS) |
| Antimicrobial Spectrum | Broad | Narrower | Some bacterial resistance |
| Toxicity | Low | High | High |
| Skin Irritation | Low | High | High |
| Water Solubility | High | Partially soluble | Low solubility |
| Applicable Industries | Personal care, medical, industrial | Personal care, industrial | Personal care |
✨ Expert Manufacturer: Developed by a team of preservative specialists
✨ High Cost-Effectiveness: Direct factory supply, lower costs
✨ Stable Supply: Sufficient production capacity and inventory
✨ Technical Support: Custom formulations and application guidance
PHMB (Polyhexamethylene Biguanide Hydrochloride), also known as Polyaminopropyl Biguanide (INCI Name), may be identified by different CAS numbers depending on the chemical description and registration system.
The commonly used CAS numbers for PHMB include:
| CAS Number | Substance Description |
|---|---|
| 32289-58-0 | Polyhexamethylene Biguanide Hydrochloride (PHMB HCl), the most commonly used CAS number for commercial PHMB products |
| 27083-27-8 | Poly(hexamethylenebiguanide) hydrochloride, another CAS number used to identify PHMB hydrochloride |
| 133029-32-0 | Polyaminopropyl Biguanide (PAPB), the INCI-related identification commonly used in cosmetic and personal care applications |
For commercial PHMB products, CAS No. 32289-58-0 is the most widely recognized identification for Polyhexamethylene Biguanide Hydrochloride.
Yes. PHMB is a polymeric antimicrobial agent widely used for controlling bacteria, fungi and algae in industrial applications.
PHMB contains biguanide groups while PHMG contains guanidine groups. They have different chemical structures and application profiles.
Easychem supplies PHMB in bulk quantities for global customers. Contact us for quotation, technical documents and sample requests.
Looking for a safe and effective preservative for your skincare line?
Contact us now to request samples, technical documents, or bulk pricing.
Suzhou easy chemical co. ltd
388, Dengyun Road,Kunshan, Jiangsu, China
Email: sales@szeasychem.com
Contact: Joyce Yu
MB: +86 13962653966
Tel: 0512- 57554186
Whatsapp&Wechat: +86 13962653966
About Us
Easychem – a manufacturer of Suzhou Easy Chemical is a professional preservative manufacturer and chemical ingredients supplier, offering for wide range of industries to global market.
Strategic partner:
Defoamer manufacturer-Invelychem
Contact
We will contact you within 2 hours, please pay attention to the email with the suffix “joyceyu@szeasychem.com”.