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Best Preservative for Powder Household Cleaners at High pH: PHMB-Based Single & Combined Systems

💬 Real Formulator’s Question:

“I’m currently working on developing a line of powder-based household cleaners and am searching for a suitable preservative solution. Since these products are in powder form and intended to be dissolved in water by the end user, I’m specifically looking for preservatives that meet the following criteria:

  • Effective in pH 7 and above

  • Available in powder form

  • Water-soluble

  • As mild and safe as possible – ideally similar in profile to Sodium Benzoate or Potassium Sorbate, but with better efficacy at higher pH

Would you be able to recommend any solutions or ingredients that could fit these requirements? I’d be truly grateful for your insight and any suggestions you might have.”

This is a question we hear more and more often as brands move toward eco-friendly powder household cleaners. Most conventional preservatives like Sodium Benzoate and Potassium Sorbate lose their effectiveness above pH 6.5, making them unsuitable for alkaline cleaning products.

In this article, we’ll share the most effective preservative for powder household cleaners, with options that are:

  • ✅ Stable and effective at pH 7 and above

  • ✅ Supplied in powder form

  • Water-soluble after reconstitution

  • ✅ As mild and safe as possible — ideal for consumer-friendly household applications

We’ll explore both single-preservative solutions and synergistic blends, so you can confidently formulate a long-lasting, microbially safe powder cleaner.

Option 1: Single-Preservative Solution — PHMB Powder

The most promising standalone solution is PHMB (Polyhexamethylene Biguanide) in powder form.

Why PHMB Works:

  • ✅ Effective at pH 4–10

  • ✅ Broad-spectrum antimicrobial against bacteria, fungi, and yeasts

  • ✅ Stable in powder form and easily soluble in water

  • ✅ Safe and mild, used in wound care, contact lenses, and sanitizers

  • ✅ Low usage concentration (0.05–0.1% after dilution)

  • Formulation Tip:

    For enhanced stability and performance, pair PHMB with a chelating agent like Sodium Gluconate (see below), especially in hard water environments.

PHMB powder
PHMB powder

Best Use Cases:

  • Laundry powders

  • Surface and floor cleaners

  • General-purpose alkaline cleaning powders

Option 2: Synergistic Preservative System — PHMB + Sodium Gluconate ± Sodium Pyrithione

For tougher microbial challenges, or to target mold and fungi more aggressively, a combination system is ideal.

System Components:

1. PHMB

  • Core antimicrobial agent (0.05–0.1%)

2. Sodium Gluconate

  • Food-grade chelator, improves preservative stability

  • Enhances performance in metal-ion-rich environments

  • Typical use level: 0.5–1%

3. Sodium Pyrithione (Optional)

  • Strong antifungal/antimold agent

  • Effective at pH 3–10

  • Use at 0.05–0.1%

  • Use with caution in regions with regulatory restrictions (e.g., EU)

  •  

ZPT powder

Benefits of the Synergistic System:

  • Broader spectrum protection

  • ✅ More robust against fungal and mold contamination

  • ✅ More stable in complex powder formulations

  • ✅ Still 100% water-soluble and powder-compatible

Comparison of Preservative Options for Powder-Based Household Cleaners

FeaturePHMB OnlyPHMB + Sodium GluconatePHMB + Gluconate + Pyrithione
pH Compatibility4–104–103–10
Antibacterial✔✔✔✔✔
Antifungal⚠ Moderate✔ Good✔✔ Excellent
Powder Stability✔✔✔✔
Regulatory Simplicity✔✔⚠ Under Regulatory Review
Best ForGeneral Cleaning UseHigh Hardness Water FormulationsHigh Humidity / Fungal-Prone Environments

Formulation Examples

Example 1: Basic Alkaline Powder Cleaner

  • PHMB 0.08%

  • Sodium Gluconate 0.5%
    → Stable, effective, safe for general household use

Example 2: Mold-Prone Bathroom Cleaner Powder

  • PHMB 0.05%

  • Sodium Gluconate 1%

  • Sodium Pyrithione 0.05%
    → Maximum antimicrobial spectrum with long-term protection

Final Recommendation: Choose Based on Your Product’s Needs

  • For basic, cost-effective protection → Use PHMB alone

  • For higher microbial challenge or better long-term stability → Use PHMB + Sodium Gluconate

  • For anti-mold and anti-fungal assurance → Add Sodium Pyrithione to the blend

All three ingredients are available in powder form, are water-soluble, and can be pre-mixed in your dry cleaning formulas.

We Supply These Ingredients

At EasyChem, we supply these ingredients with full technical support, SDS/TDS, and global shipping.:

👉 [Request Samples]
👉 [Get a Quote]
👉 [Download TDS]

Let us help you build a safe, effective, and stable powder cleaner formulation.

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